How Does Our Blood-Sugar Level Affect Our Circulation?
To begin, we know that glycation is defined as the random binding of sugar molecules to the proteins or fats in our body. Thus, glycation ties up lots of useful cellular and circulating molecules that support life. In fact, the accumulation of Advanced Glycation End-products (AGE's) is widely regarded as one of the key triggers of aging.
But how does this affect circulation? Putting all the pieces of the jigsaw together, current research now shows that sugar molecules in your bloodstream may be able to bind with the well-known clotting protein, fibrin. Fibrin then becomes denser and more like a tight knot. This makes fibrin very difficult break down. Normally, the fibrinolytic molecules circulating in your blood break down fibrin and keep your blood flowing. When this process is slowed due to the denser nature of fibrin, more knots of fibrin build up and block your blood flow, and the circulation to your eyes, kidneys, brain, and limbs may begin a long decline.
In summary, as blood sugar levels go up, the random biochemical process known as glycation is now believed to have a dramatic influence on fibrin. When your blood sugar goes up, then your glycation levels increase, and the fibrin clots in your blood tend to become denser and less easily dissolved than the clots of those with lower blood-sugar levels.
Our fundamental view is that the balancing of blood sugar levels following meals not only will lead to healthier (lower) glycation levels, but will benefit other parameters of good health.
A question of serious importance is this: given that many individuals already have significant levels of blockage of the tiny capillaries in their body and are at risk for serious health problems, can the clotting be reversed? We believe that various proteolytic enzymes may be able to break down these dense, difficult-to-dissolve blood clots that your body cannot naturally dissolve. There is research suggesting that several proteolytic enzymes available as dietary supplements, taken for a number of months, may do exactly that.
The only caveat I know of is this: if you have any wounds (from surgery or accidents or dental work) that are healing, you may want to avoid supplemental proteolytic enzymes until healing is well advanced. Until then, you need clotting. In fact, when proteolytic enzymes levels in your blood are too high, fibrin will break down as fast as it is being formed, and there may be increased bleeding and slower healing.
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